Mark Foundation for Cancer Research - Project proposals

The Mark Foundation for Cancer Research is dedicated to accelerating exciting academic discoveries into new therapies and platforms that will substantially improve outcomes for cancer patients. Currently, there are few options for academic scientists to obtain the resources and know-how to advance drug discovery efforts for promising new cancer targets.
To stem this gap, The Mark Foundation has established the Drug Discovery Award program. Through this program, The Mark Foundation aligns with investigators working to discover and progress a new therapeutic agent into preclinical development, providing not only resources to support post-target validation through early lead development but also the expertise of seasoned biopharma R&D scientists who will advise on activities on the critical path to developing a new therapeutic agent.
The application process begins with a concept letter stage consisting of a 2-page description of the project. The concept letter submission portal opens on September 18, 2024, and letters are due by November 11, 2024. Invitations for full applications will be issued in January 2025.
Award Details

  • Applicants may request funding to support a total budget of up to $1,000,000 for a period of 12-36 months.
  • The budget limit includes both direct and indirect costs, with indirect costs not to exceed 10% of the direct costs.
  • The budget and duration requested for the grant must match a realistic estimate of the cost and timeline for the proposed work.
  • The proposed work must carry the project forward to a well-defined milestone/value inflection point (e.g., identification of a potent and selective lead or demonstration of in vivo efficacy)
  • Some or all of the proposed work may be carried out at approved contract research organizations (CROs)
Eligible therapeutic modalities:
  • Large molecules / biologics
  • Small molecules (including heterobifunctionals)
  • Peptides
  • Conjugates (ADC, radioconjugates)
  • Nucleic acids (ASO, RNA)
for further details please follow this link :  https://themarkfoundation.org/drug-discovery-award-3/